故事主要聚焦在一个早熟的男孩和他的选择性缄默的兄弟身上。在家庭因毒品贩子的干预而瓦解后，两兄弟开始了一场关于爱、救赎和报复的冒险。

职场“女强人”胡小妮遇到问题总习惯过度放大，老公何向南表面耙耳朵、实则睿智有担当，生来就是为老婆平事的存在。可是刚抚平老婆的焦虑，两个机灵可爱好动的孩子又添上新乱，再加上社恐二次元的小姑子何颜、自来熟的小舅子胡非，以及宠婿狂魔的岳母和怼天怼地怼全家的岳父，这个机动大家庭每天都在上演一出出好戏。三代之间的“相互较量”、亲家之间的微妙关系、邻里之间的插科打诨，呈现出啼笑皆非的人间烟火气，在喜乐中找到生活的智慧，讲述新时代下南方城市美好家庭的故事。

　　Mike meijubar.net Biggs(Billy Gardell饰)是一个体型稍显肥胖却心地善良的芝加哥警员，于一次偶然的机会在肥胖人士匿名交友会结识了同样体型丰满的小学老师Molly Flynn(Melissa McCarthy饰)。二人从相识、相恋一路走来，和家人、朋友之间发生了无数令人捧腹的囧事。然而每一次啼笑皆非的状况背后，却总是氤氲着暖暖的温情。正如Mike的搭档Carl McMillan(Reno Wilson饰)所说，他们之所以拥有稍显庞大的身躯，是为了能够装得下他们宽广的心。
　　在第一季末，Mike终于克服了自己的承诺恐惧症，在与Molly交往七个月后，将那枚在他们相识后两周就买下的订婚戒指交给了她。二人的婚后生活又会碰撞出怎样的火花，尽请期待9月27日回归的Mike and Molly第二季。

　　NUMB3RS is a drama about FBI agent Don Eppes (Rob Morrow), who recruits his mathematical-genius brother, Charlie (David Krumholtz) to help the Bureau solve a wide range of challenging crimes in Los Angeles. The two brothers take on the most confounding criminal cases from a very distinctive perspective.
　　
　　Inspired by actual cases, the series depicts how the confluence of police work and mathematics provides unexpected revelations and answers to the most perplexing criminal questions.
　　
　　A dedicated FBI agent, Don couldn't be more different from his younger brother, Charlie, a brilliant mathematician who, since he was little, has yearned to impress his big brother. As a seasoned investigator, Don deals in hard facts and evidence, whereas Charlie, a math professor at a California university, functions in a world of mathematical probability and equations.
　　
　　Now, despite their disparate approaches to life, Don and Charlie are able to combine their areas of expertise and solve some killer cases.

　　久居草药寨的板蓝根精怪小蓝（林小宅 饰），意外救下了竟能突破草药寨结界的医官阿九（潘毅鸿 饰），谁知阿九除了是备受敬仰的“九神医”，更有隐藏身份——抓捕草药精怪的上清司统领玖冥。小蓝与阿九意外结为同死同伤的灵配关系，就此展开了一场猫鼠游戏，并由此揭开了二人前世今生的两世牵绊。